Reframe Daily: One nutrition tweak cut kids’ post-surgery gut infections from 29% to 7%—plus new breathing training for Parkinson’s

Reframe Daily—curated by Christin Chong (neuroscience PhD, Buddhist chaplain, healthtech strategy consultant)—delivers optimistic and credible health research updates you won’t find in most popular news outlets, from sources scientists and healthcare providers read and trust.

Today in one sentence: Kids given extra nutrition before Hirschsprung surgery had far fewer serious gut infections, Parkinson’s patients improved fitness with breathing-muscle training, one-dose Gardasil 9 stayed strongly immune for years, a sham-controlled trial found brain-stimulation benefits for adult ADHD, and a manganese-boosted probiotic fought colorectal cancer in preclinical tests.

Christin’s Note: THANK YOU FOR ALL YOUR SUPPORT IN 2025! I am amazed by the steady growth of this newsletter and how it remains at a open rate of 41.8% (not sure if my personal emails even get read at this %!) I will be on a road trip for the remainder of the year and Reframe Daily will return January 5th Monday. Take care ‘til then!

Good news: Kids who got extra nutrition before Hirschsprung surgery had way fewer dangerous bowel infections after surgery (about 7% vs 29%), and no bad side effects were reported.

Preoperative nutritional support in children with Hirschsprung disease: a prospective multicenter open-label randomized controlled trial

Market readiness: 🙂🙂🙂🙂🙂 (This is a care approach hospitals can use now in the US using existing nutrition support—no new product approval needed.)

Good news: A simple breathing-muscle workout helped people with Parkinson’s use more oxygen during exercise, be more active, and report better quality of life.

Effects of inspiratory muscle training on oxygen consumption, muscle oxygen, and physical activity levels in patients with Parkinson’s disease

Market readiness: 🙂🙂🙂🙂🙂 (Inspiratory muscle training devices and rehab programs already exist in the US; this study supports using them for Parkinson’s patients.)

Good news: One dose of the HPV vaccine Gardasil 9 still kept strong antibody levels for years, which could make it easier and cheaper to protect more girls.

Immunogenicity of one and two doses of Gardasil®9 in Tanzanian girls in the DoRIS Trial

Market readiness: 🙂🙂🙂🙂 (Gardasil 9 is already available in the US, but moving to a standard 1-dose schedule would likely require guideline/label changes.)

Good news: A gentle brain-stimulation treatment (tACS) showed benefit and safety in a sham-controlled trial for adults with ADHD, hinting at a future non-drug option.

Efficacy and safety of transcranial alternating current stimulation in adults with attention deficit hyperactivity disorder: a double-blind randomized sham-controlled trial

Market readiness: 🙂🙂🙂 (Human trial evidence exists, but it’s not a standard FDA-cleared, widely available ADHD treatment yet—likely needs larger studies and regulatory steps.)

Good news: In animal studies, an “upgraded” probiotic helped slow colon cancer growth and spread, and it also boosted the immune response—promising for future pill-like treatments.

Manganese-engineered Lactobacillus Reuteri with enhanced antitumor and immunomodulatory activities for colorectal cancer prevention and treatment

Market readiness: 🙂 (This is still preclinical—tested in animals, not yet in human trials or on the US market.)

Thank you for taking the time to take care of yourself and your loved ones.